Dormancy and subsequent activation
caused by weakened immune system

It is believed that years can pass before symptoms appear in a patient that has been infected with Borrelia. In 1998, a study conducted in Switzerland demonstrated that only 12.5% of the patients that tested positive for Borrelia developed clinical symptoms confirming that Borrelia burgdorferi infection is often asymptomatic. A report from Germany outlines the case of a 12 year old boy that developed Lyme Arthritis 5 years after being bit by a tick. The case indicates that the latency period between tick bite and onset of Lyme Arthritis may last up to 5 years.

All asymptomatic carriers of Borrelia are at risk of developing Lyme disease at some point. Stress, an increasing health concern for physicians worldwide, may have been the trigger that activated Lyme disease in a patient in Sweden. The case is reported of a 26 year old woman with latent Lyme borreliosis that was concurrently activated with a herpes simplex virus type 1 infection. Immune suppression by stress may have caused activation of both infections.